There are 3 US Post Offices in Carlisle County serving a total of 4,995 residents equating to 1,665 residents per post office. It's estimated that approximately 7,973 packages are handled across the 3 county post offices annually. Carlisle County is a county located in the U.S. state of Kentucky. As of the 2010 census, the population was 5,104, making it the fourth-least populous county in Kentucky. Its county seat is Bardwell. The county was founded in 1886 and named for John Griffin Carlisle, a Speaker of the United States House of Representatives from Kentucky. Carlisle County is a prohibition or dry county."