There are 20 US Post Offices in Lee County serving a total of 334,869 residents equating to 16,743 residents per post office. It's estimated that approximately 534,488 packages are handled across the 20 county post offices annually. Lee County is a county in the State of Florida. As of the 2010 census, the population was 618,754. The county seat is Fort Myers, and the largest city is Cape Coral. Lee County comprises the Cape Coral-Fort Myers, FL Metropolitan Statistical Area."