There are 21 US Post Offices in Tioga County serving a total of 42,613 residents equating to 2,029 residents per post office. It's estimated that approximately 68,015 packages are handled across the 21 county post offices annually. Tioga County is a county located in the U.S. state of Pennsylvania. As of the 2010 census, the population was 41,981. Its county seat is Wellsboro. The county was created on March 26, 1804, from part of Lycoming County and later organized in 1812. It is named for the Tioga River.