There are 9 US Post Offices in Tallahatchie County serving a total of 13,954 residents equating to 1,550 residents per post office. It's estimated that approximately 22,272 packages are handled across the 9 county post offices annually. Tallahatchie County is a county located in the U.S. state of Mississippi. As of the 2010 census, the population was 15,378. Its county seats are Charleston and Sumner. Tallahatchie County is located in the Mississippi Delta region. It is divided by the Tallahatchie River, which runs from north to south through the county before joining what becomes the Yazoo River in LeFlore County."