There are 7 US Post Offices in Panola County serving a total of 36,110 residents equating to 5,159 residents per post office. It's estimated that approximately 57,636 packages are handled across the 7 county post offices annually. Panola County is a county located in the U.S. state of Mississippi. As of the 2010 census, the population was 34,707. Its county seats are Sardis and Batesville. Panola is a Cherokee word which means cotton. The county is located just east of the Mississippi Delta and bisected by the Tallahatchie River flowing to the southwest, separating the two county seats."