There are 14 US Post Offices in Calhoun County serving a total of 96,977 residents equating to 6,927 residents per post office. It's estimated that approximately 154,786 packages are handled across the 14 county post offices annually. Calhoun County is a county in the U.S. state of Alabama. As of the 2010 census, the population was 118,572. Its county seat is Anniston. Its name is in honor of John C. Calhoun, famous member of the United States Senate from South Carolina. Calhoun County is included in the Anniston-Oxford Metropolitan Statistical Area.