There are 9 US Post Offices in Wetzel County serving a total of 17,036 residents equating to 1,893 residents per post office. It's estimated that approximately 27,191 packages are handled across the 9 county post offices annually. Wetzel County is a county located in the U.S. state of West Virginia. As of the 2010 census, the population was 16,583. Its county seat is New Martinsville. The county, founded in 1846, is named for Lewis Wetzel, a famous frontiersman and Indian fighter. Its northern border aligns with the Mason-Dixon line but is to the west of the actual Mason-Dixon line."