There are 11 US Post Offices in Cherokee County serving a total of 61,616 residents equating to 5,601 residents per post office. It's estimated that approximately 98,346 packages are handled across the 11 county post offices annually. Cherokee County is a county located in the U.S. state of Texas. As of the 2010 census, its population was 50,845 . The county seat is Rusk. The county was named for the Cherokee, who lived in the area before being expelled in 1839. Rusk, the county seat, is 130 miles southeast of Dallas and 160 miles north of Houston. Cherokee County comprises the Jacksonville, TX Micropolitan Statistical Area, which is also included in the Tyler-Jacksonville, TX Combined Statistical Area."