There are 9 US Post Offices in Mayes County serving a total of 39,384 residents equating to 4,376 residents per post office. It's estimated that approximately 62,861 packages are handled across the 9 county post offices annually. Mayes County is a county located in the U.S. state of Oklahoma. As of the 2010 census, the population was 41,259. Its county seat is Pryor Creek, Oklahoma. Named for Samuel Houston Mayes, Principal Chief of the Cherokee Nation from 1895 to 1899, it was originally created at the Sequoyah Convention in August 1905."