There are 22 US Post Offices in Cheshire County serving a total of 74,943 residents equating to 3,407 residents per post office. It's estimated that approximately 119,617 packages are handled across the 22 county post offices annually. Cheshire County is a county located in the southwestern portion of the U.S. state of New Hampshire. As of the 2010 census, the population was 77,117. Its county seat is Keene. Cheshire was one of the five original counties of New Hampshire, and is named for the county of Cheshire in England. It was organized in 1771 at Keene. Cheshire County comprises the Keene, NH Micropolitan Statistical Area."