There are 5 US Post Offices in Nuckolls County serving a total of 1,886 residents equating to 377 residents per post office. It's estimated that approximately 3,010 packages are handled across the 5 county post offices annually. Nuckolls County is a county located in the U.S. state of Nebraska. As of the 2010 census, the population was 4,500. Its county seat is Nelson. In the Nebraska license plate system, Nuckolls County is represented by the prefix 42 (it had the forty-second-largest number of vehicles registered in the county when the license plate system was established in 1922)."