There are 8 US Post Offices in Wayne County serving a total of 14,447 residents equating to 1,806 residents per post office. It's estimated that approximately 23,059 packages are handled across the 8 county post offices annually. Wayne County is a county located in the Ozark foothills in the U.S. state of Missouri. As of the 2010 census, the population was 13,521. The county seat is Greenville. The county was officially organized on December 11, 1818, and is named after General \"Mad\" Anthony Wayne who served in the American Revolutionary War."