There are 8 US Post Offices in Appanoose County serving a total of 13,022 residents equating to 1,628 residents per post office. It's estimated that approximately 20,785 packages are handled across the 8 county post offices annually. Appanoose County is a county located in the U.S. state of Iowa. As of the 2010 census, the population was 12,884. Its county seat is Centerville. The county was once a major coal-mining region. In recent decades, the state has made a mostly-unsuccessful effort to develop manufacturing as an alternate form of employment. A Rubbermaid plant was the county's largest private employer until the company announced, in June 2006, that the plant, located in the Centerville industrial park, would relocate to Winfield, Kansas in October of that year. As a result of the closure and the failure of local officials to recruit new employers to the county, unemployment in Appanoose County has consistently ranked among the highest in the state of Iowa."